Publications:
Freake, HC, KE Govoni, K Guda, C Huang and SA Zinn. 2001. Actions and interactions of thyroid hormones and zinc status in growing rats. J Nutr 131:1135-1141.
Phillips, AL, C Faustman, MP Lynch, KE Govoni, TA Hoagland and SA Zinn. 2001. Effects of dietary a-tocopherol supplementation on color and lipid stability in pork. Meat Science 58:389-393.
Rausch, MI, MW Tripp, KE Govoni, W Zang, WJ Weber, BA Crooker, TA Hoagland and SA Zinn. 2002. Limit feeding and somatotropin supplementation in growing beef cattle. J Anim Sci 80:94-100.
Govoni, KE, XC Tian, GW Kazmer, M Taneja, B Enright, AL Rivard, X Yang and SA Zinn. 2002. Age-related changes of the somatotropic axis in cloned Holstein calves. Biol of Reprod 66:1293-1298.
Govoni, KE, Hoagland, TA, and Zinn, SA. 2003. The ontogeny of the somatotropic axis in male and female Hereford calves from birth to one year of age. J Anim Sci 81:2811-2817.
Govoni, KE, Hoagland, TA, and Zinn, SA. 2004. The ontogeny of the somatotropic axis in Hereford calves from birth to one year of age and its response to administration of exogenous bovine somatotropin. J Anim Sci 82:1646-1655.
Govoni, KE, Baylink, DJ, and Mohan, S. 2005. The multi-functional role of insulin-like growth factor binding proteins in bone. Pediatr Nephrol 20:261-268.
Govoni, KE, Kramer, A, Winter, E, Amaar, YG, Baylink, DJ, and Mohan, S. 2005 In Press. Regulation of insulin-like growth factor binding protein (IGFBP)-5, four and a half lim (FHL)-2, and a disintegrin and metalloprotease (ADAM)-9 expression in osteoblasts. Growth Hormone and IGF Research 16:49-56. Epub 2005 Nov 28.
Govoni, KE, Lee, SK, Chadwick, RB, Yu, H, Kasukawa, Y, Baylink, DJ, and Mohan, S. 2006. Whole Genome Microarray Analysis of the In Vivo Effects of a Single Effective GH Dose on Gene Expression in Bones of GH-Deficient lit/lit Mice: GH regulates T-box3, a Novel Transcription Factor, Independent of IGF-I. Am J Physiol Endocrinol Metab 291:E128-36. Epub 2006 Feb 7.
Govoni, KE, Baylink, DJ, Chen, J, and Mohan, S. 2006. Disruption of four and a half LIM domain (FHL)-2 decreases bone mineral content and bone mineral density in femur and tibia bones of female mice. Cal Tissue Int 79:112-7. Epub 2006 Aug 15.
Govoni, KE, Lee, SK, Chung, YS, Behringer, RR, Wergedal, JE, Baylink, DJ, and Mohan, S. 2007. Disruption of insulin-like growth factor (IGF)-I expression in type IIaI collagen expressing cells reduces bone length and width in mice. Physiol Genomics 30:354-62 Epub 2007 May 22.
Velayudhan, BT, Govoni, KE, Hoagland, TA, and Zinn, SA. 2007. Growth rate and concentrations of the somatotropic axis in beef cattle administered exogenous bovine somatotropin beginning at 200, 250 and 300 days of age. J Anim Sci 85:2886-72.
Govoni, KE, Wergedal, JE, Florin, L, Angel P, Baylink, DJ, and Mohan, S. 2007. Conditional Deletion of IGF-I in Collagen Type 1α2 (Col1α2) Expressing Cells Results In Postnatal Lethality and a Dramatic Reduction in Bone Accretion. Endocrinology 148:8706-15 Epub 2007 Aug 23.
Govoni, KE, Donahue LR, Marden C, Mohan S. 2008. Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #A/J/NaJ chromosome substitution strains. Physiol Genomics. 35:159-64. Epub 2008 Aug 5.
Govoni, KE, Wergedal, JE, Chadwick, RB, Srivistava, AK, and Mohan, S. 2008. Pre-pubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice. Am J Physiol Endocrinol Metab 295:E1172-80. Epub 2008 Sep 23.
Govoni, KE, Linares, GR, Chen, ST, Pourteymoor, S, and Mohan, S. 2009. T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2. J Cell Biochem 106:482-90.
Linares, GR, Xing, W, Govoni, KE, Chen, ST, and Mohan, S. 2009. Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress. Bone 44:795-804. Epub 2009 Jan 14.
Govoni, KE, Goodman, D, Maclure RM, Penfold, LM, and Zinn, SA. 2011. Serum concentrations of insulin-like growth factor and insulin-like growth factor binding protein-2 and -3 in eight hoofstock species. Zoo Biol 30:275-84.
Govoni, KE. 2012. Insulin-like growth factor-I molecular pathways in osteoblasts: Potential targets for pharmacological manipulation. Curr Mol Pharmacol 5:143-52.
Xing W, Govoni KE, Donahue LR, Kesavan C, Wergedal J, Long C, Bassett JH, Gogakos A, Wojcicka A, Williams GR, Mohan S. 2012. Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice. J Bone Miner Res 27:1067-79.
Glynn, E, Alfredo, S-L, Zinn, S, Hoagland, T, Govoni, KE. 2013. Culture conditions for equine bone marrow mesenchymal stem cells and expression of key transcription factors during their differentiation into osteoblasts. J Anim Sci Biotechnol 4:40
Hoffman, ML, McFadden, KK, Hoagland, T, Kazmer, G, Govoni, KE. 2014. Short communication: Expression of T-box 2 and 3 in the bovine mammary gland. J Dairy Sci. 97:4322-8.
Hoffman, ML, Rokossa, MA, Zinn, S, Hoagland, T, Govoni, KE. 2014. Poor maternal nutrition during gestation in sheep reduces circulating concentrations of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 in offspring. Domest Anim Endocrinol May 28;49C:39-48. doi: 10.1016/j.domaniend.2014.05.002
Reed, SA, Raja, JS, Hoffman, ML, Zinn, S, Govoni, KE. Poor maternal nutrition inhibits muscle development in ovine offspring. Submitted to J Anim Sci Biotechn on June 5, 2014. J Anim Sci Biotechnol. 2014 Sep 5;5(1):43.
Harvey, BM, Eschbach, M, Ackell, E, Kotha, S, Darre, M, Adamson, D, Ramanathan, R, Mancini, R, Govoni, KE. 2015. Effect of daily lithium chloride administration on bone quality and strength in growing broiler chickens Poultry Sci Poult Sci. Feb;94(2):296-301.
Govoni, KE. 2015. Use of mesenchymal stem cells in bone repair. J Anim Sci. Mar;93(3):871-878.
Jones, AK, Gately, RE, McFadden, KK, Zinn, SA, Govoni, KE, and Reed, SA. 2016. Transabdominal ultrasound for detection of pregnancy, fetal and placental landmarks, and fetal age before day 45 of gestation in the sheep. Theriogenology 85:939-945.
Raja, JS, Hoffman, ML, Govoni, KE, Zinn, SA, and Reed, SA. 2016. Restricted maternal nutrition alters myogenic regulatory factor expression in satellite cells of ovine offspring. Animal 10:1200-1203.
Hoffman, ML, Peck, KN, Forella, ME, Fox, AR, Govoni, KE, and Zinn, SA. 2016. The effects of poor maternal nutrition during gestation on postnatal growth and development of lambs. J Anim Sci. 94:789-799.
Hoffman, ML, Peck, KP, Wegrzyn, JL, Reed, SA, Zinn, SA, and Govoni, KE. 2016. Poor maternal nutrition during gestation alters the expression of genes involved in muscle development and metabolism in lambs. J Anim Sci. 94:3093-3099.
Pillai, SM, Sereda, NH, Hoffman, ML, Valley, EV, Crenshaw, TD, Park, YK, Lee, JY, Zinn, SA, and Govoni, KE. 2016. Effects of poor maternal nutrition during gestation on bone development and mesenchymal stem cell activity in offspring. PLos One 11: doi: 10.1371/journal.pone.0168382.
Pillai, SM, Jones, AK, SM, Hoffman, ML, McFadden, KK, Reed, SA, Zinn, SA, and Govoni, KE. 2017. Fetal and organ development at gestational days 45, 90, 135 and at birth of lambs exposed to under- or over-nutrition during gestation. Translational Animal Science. doi:10.2527/jas2016.0002.
Hoffman, ML, Reed, SA, Pillai, SM, Jones, AK, McFadden, KK, Zinn, SA, and Govoni, KE. 2017. Invited Symposium Review: The effects of poor maternal nutrition during gestation on offspring postnatal growth and metabolism. J Anim Sci. Minor Revision Required, In Progress.
Jones, AK, Gately, RE, McFadden, KK, Zinn, SA, Govoni, KE, and Reed, Sa. 2017. Ultrasound during mid-gestation: Agreement with physical fetal and placental measurements and use in predicting gestational age in sheep. Reprod in Dom Anim. Revised version under review.
Freake, HC, KE Govoni, K Guda, C Huang and SA Zinn. 2001. Actions and interactions of thyroid hormones and zinc status in growing rats. J Nutr 131:1135-1141.
Phillips, AL, C Faustman, MP Lynch, KE Govoni, TA Hoagland and SA Zinn. 2001. Effects of dietary a-tocopherol supplementation on color and lipid stability in pork. Meat Science 58:389-393.
Rausch, MI, MW Tripp, KE Govoni, W Zang, WJ Weber, BA Crooker, TA Hoagland and SA Zinn. 2002. Limit feeding and somatotropin supplementation in growing beef cattle. J Anim Sci 80:94-100.
Govoni, KE, XC Tian, GW Kazmer, M Taneja, B Enright, AL Rivard, X Yang and SA Zinn. 2002. Age-related changes of the somatotropic axis in cloned Holstein calves. Biol of Reprod 66:1293-1298.
Govoni, KE, Hoagland, TA, and Zinn, SA. 2003. The ontogeny of the somatotropic axis in male and female Hereford calves from birth to one year of age. J Anim Sci 81:2811-2817.
Govoni, KE, Hoagland, TA, and Zinn, SA. 2004. The ontogeny of the somatotropic axis in Hereford calves from birth to one year of age and its response to administration of exogenous bovine somatotropin. J Anim Sci 82:1646-1655.
Govoni, KE, Baylink, DJ, and Mohan, S. 2005. The multi-functional role of insulin-like growth factor binding proteins in bone. Pediatr Nephrol 20:261-268.
Govoni, KE, Kramer, A, Winter, E, Amaar, YG, Baylink, DJ, and Mohan, S. 2005 In Press. Regulation of insulin-like growth factor binding protein (IGFBP)-5, four and a half lim (FHL)-2, and a disintegrin and metalloprotease (ADAM)-9 expression in osteoblasts. Growth Hormone and IGF Research 16:49-56. Epub 2005 Nov 28.
Govoni, KE, Lee, SK, Chadwick, RB, Yu, H, Kasukawa, Y, Baylink, DJ, and Mohan, S. 2006. Whole Genome Microarray Analysis of the In Vivo Effects of a Single Effective GH Dose on Gene Expression in Bones of GH-Deficient lit/lit Mice: GH regulates T-box3, a Novel Transcription Factor, Independent of IGF-I. Am J Physiol Endocrinol Metab 291:E128-36. Epub 2006 Feb 7.
Govoni, KE, Baylink, DJ, Chen, J, and Mohan, S. 2006. Disruption of four and a half LIM domain (FHL)-2 decreases bone mineral content and bone mineral density in femur and tibia bones of female mice. Cal Tissue Int 79:112-7. Epub 2006 Aug 15.
Govoni, KE, Lee, SK, Chung, YS, Behringer, RR, Wergedal, JE, Baylink, DJ, and Mohan, S. 2007. Disruption of insulin-like growth factor (IGF)-I expression in type IIaI collagen expressing cells reduces bone length and width in mice. Physiol Genomics 30:354-62 Epub 2007 May 22.
Velayudhan, BT, Govoni, KE, Hoagland, TA, and Zinn, SA. 2007. Growth rate and concentrations of the somatotropic axis in beef cattle administered exogenous bovine somatotropin beginning at 200, 250 and 300 days of age. J Anim Sci 85:2886-72.
Govoni, KE, Wergedal, JE, Florin, L, Angel P, Baylink, DJ, and Mohan, S. 2007. Conditional Deletion of IGF-I in Collagen Type 1α2 (Col1α2) Expressing Cells Results In Postnatal Lethality and a Dramatic Reduction in Bone Accretion. Endocrinology 148:8706-15 Epub 2007 Aug 23.
Govoni, KE, Donahue LR, Marden C, Mohan S. 2008. Complex genetic regulation of bone mineral density and insulin-like growth factor-I in C57BL/6J-Chr #A/J/NaJ chromosome substitution strains. Physiol Genomics. 35:159-64. Epub 2008 Aug 5.
Govoni, KE, Wergedal, JE, Chadwick, RB, Srivistava, AK, and Mohan, S. 2008. Pre-pubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice. Am J Physiol Endocrinol Metab 295:E1172-80. Epub 2008 Sep 23.
Govoni, KE, Linares, GR, Chen, ST, Pourteymoor, S, and Mohan, S. 2009. T-box 3 negatively regulates osteoblast differentiation by inhibiting expression of osterix and runx2. J Cell Biochem 106:482-90.
Linares, GR, Xing, W, Govoni, KE, Chen, ST, and Mohan, S. 2009. Glutaredoxin 5 regulates osteoblast apoptosis by protecting against oxidative stress. Bone 44:795-804. Epub 2009 Jan 14.
Govoni, KE, Goodman, D, Maclure RM, Penfold, LM, and Zinn, SA. 2011. Serum concentrations of insulin-like growth factor and insulin-like growth factor binding protein-2 and -3 in eight hoofstock species. Zoo Biol 30:275-84.
Govoni, KE. 2012. Insulin-like growth factor-I molecular pathways in osteoblasts: Potential targets for pharmacological manipulation. Curr Mol Pharmacol 5:143-52.
Xing W, Govoni KE, Donahue LR, Kesavan C, Wergedal J, Long C, Bassett JH, Gogakos A, Wojcicka A, Williams GR, Mohan S. 2012. Genetic evidence that thyroid hormone is indispensable for prepubertal insulin-like growth factor-I expression and bone acquisition in mice. J Bone Miner Res 27:1067-79.
Glynn, E, Alfredo, S-L, Zinn, S, Hoagland, T, Govoni, KE. 2013. Culture conditions for equine bone marrow mesenchymal stem cells and expression of key transcription factors during their differentiation into osteoblasts. J Anim Sci Biotechnol 4:40
Hoffman, ML, McFadden, KK, Hoagland, T, Kazmer, G, Govoni, KE. 2014. Short communication: Expression of T-box 2 and 3 in the bovine mammary gland. J Dairy Sci. 97:4322-8.
Hoffman, ML, Rokossa, MA, Zinn, S, Hoagland, T, Govoni, KE. 2014. Poor maternal nutrition during gestation in sheep reduces circulating concentrations of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-3 in offspring. Domest Anim Endocrinol May 28;49C:39-48. doi: 10.1016/j.domaniend.2014.05.002
Reed, SA, Raja, JS, Hoffman, ML, Zinn, S, Govoni, KE. Poor maternal nutrition inhibits muscle development in ovine offspring. Submitted to J Anim Sci Biotechn on June 5, 2014. J Anim Sci Biotechnol. 2014 Sep 5;5(1):43.
Harvey, BM, Eschbach, M, Ackell, E, Kotha, S, Darre, M, Adamson, D, Ramanathan, R, Mancini, R, Govoni, KE. 2015. Effect of daily lithium chloride administration on bone quality and strength in growing broiler chickens Poultry Sci Poult Sci. Feb;94(2):296-301.
Govoni, KE. 2015. Use of mesenchymal stem cells in bone repair. J Anim Sci. Mar;93(3):871-878.
Jones, AK, Gately, RE, McFadden, KK, Zinn, SA, Govoni, KE, and Reed, SA. 2016. Transabdominal ultrasound for detection of pregnancy, fetal and placental landmarks, and fetal age before day 45 of gestation in the sheep. Theriogenology 85:939-945.
Raja, JS, Hoffman, ML, Govoni, KE, Zinn, SA, and Reed, SA. 2016. Restricted maternal nutrition alters myogenic regulatory factor expression in satellite cells of ovine offspring. Animal 10:1200-1203.
Hoffman, ML, Peck, KN, Forella, ME, Fox, AR, Govoni, KE, and Zinn, SA. 2016. The effects of poor maternal nutrition during gestation on postnatal growth and development of lambs. J Anim Sci. 94:789-799.
Hoffman, ML, Peck, KP, Wegrzyn, JL, Reed, SA, Zinn, SA, and Govoni, KE. 2016. Poor maternal nutrition during gestation alters the expression of genes involved in muscle development and metabolism in lambs. J Anim Sci. 94:3093-3099.
Pillai, SM, Sereda, NH, Hoffman, ML, Valley, EV, Crenshaw, TD, Park, YK, Lee, JY, Zinn, SA, and Govoni, KE. 2016. Effects of poor maternal nutrition during gestation on bone development and mesenchymal stem cell activity in offspring. PLos One 11: doi: 10.1371/journal.pone.0168382.
Pillai, SM, Jones, AK, SM, Hoffman, ML, McFadden, KK, Reed, SA, Zinn, SA, and Govoni, KE. 2017. Fetal and organ development at gestational days 45, 90, 135 and at birth of lambs exposed to under- or over-nutrition during gestation. Translational Animal Science. doi:10.2527/jas2016.0002.
Hoffman, ML, Reed, SA, Pillai, SM, Jones, AK, McFadden, KK, Zinn, SA, and Govoni, KE. 2017. Invited Symposium Review: The effects of poor maternal nutrition during gestation on offspring postnatal growth and metabolism. J Anim Sci. Minor Revision Required, In Progress.
Jones, AK, Gately, RE, McFadden, KK, Zinn, SA, Govoni, KE, and Reed, Sa. 2017. Ultrasound during mid-gestation: Agreement with physical fetal and placental measurements and use in predicting gestational age in sheep. Reprod in Dom Anim. Revised version under review.